Low density Nickel-Iminodiacetic acid (IDA) crosslinked agarose resin. The lower amount of available groups allows for higher selectivity/specificity in the binding of the tagged-protein. It recognizes two exposed histidine tags. The resin works well with relatively easy to separate His-tagged proteins and is recommended for most standard purifications. Suitable for batch or column purifications. Binding/loading capacity: 5 - 20 μmol Me2+/ml gel.